The Lions are 4-0-1 in the last 5 meetings. Quarterback Kyler Murray has not beaten the Lions yet in his career. The closest he came was his NFL debut, when he rallied the Cardinals from 18 points down to finish in a tie.

Arizona Cardinals wide receiver Marvin Harrison Jr. (18) celebrates his touchdown catch against the Los Angeles Rams with Cardinals wide receivers Greg Dortch (4) and Zach Pascal (0) during the first half of an NFL football game Sunday, Sept. 15, 2024, in Glendale, Ariz. The Cardinals won 41-10. (AP Photo/Ross D. Franklin) AP

On Sunday, the Lions travel to the desert to take on Kyler Murray and the Arizona Cardinals. The Cardinals are coming off a 41-10, blowout victory over Matthew Stafford and the L.A. Rams. Murray delivered a strong performance in the Week 2 contest,