Demi Moore and Margaret Qualley Break Down the Most Disgusting Part of Wearing Those Prosthetics in 'The Substance'
The Substance stars Moore as a TV fitness guru named Elisabeth Sparkle whose boss ( Dennis Quaid) wants to replace her with someone younger—so she uses a mysterious black-market drug to create a more youthful version of herself, who goes by Sue (Qualley). If you've not yet seen it in a theater, it heads to streaming on Mubi on Oct. 31.