Primary aldosteronism management depends on a multitude of factors, and surgical adrenalectomy is generally recommended in ...

Lorundrostat, a novel therapy which blocks the production of aldosterone from the adrenal glands, demonstrated clinically meaningful and sustained reductions in blood pressure in 1,083 patients with ...

Please provide your email address to receive an email when new articles are posted on . Dysregulated aldosterone production, sometimes driven by obesity, can cause hypertension. Targeted therapies ...

Successfully met the primary endpoint in the BrigHtn trial, delivering a 20.3 mmHg reduction in systolic blood pressure (SBP), or an 11 mmHg (p-value 0.0001) decline on a placebo-adjusted basis, at 2 ...

Please provide your email address to receive an email when new articles are posted on . A seated saline suppression test had a high false-negative rate for predicting response to primary aldosteronism ...

A recent study published in the journal Scientific Reports investigated the effects of acute transcutaneous vagus nerve stimulation (tVNS) on serum aldosterone levels. Psychological stress is one of ...

Aldosterone escape and non-ACE pathways for angiotensin II production may explain, at least in part, the continued high mortality rates in heart failure patients despite the advances made in ...

Once-daily treatment with the selective aldosterone synthase inhibitor lorundrostat (Mineralys Therapeutics) safely and significantly reduced blood pressure in adults with uncontrolled hypertension in ...

A drug that has been used to slow progression of kidney and cardiovascular disease in people with type 2 diabetes may also help people with chronic kidney disease who do not have diabetes, according ...

Hyperaldosteronism is when one or both adrenal glands release too much of the hormone aldosterone. High blood pressure can result, which could lead to atrial fibrillation, heart attack, or stroke.