KATMAP: A new way to understand and predict gene splicing

Although heart cells and skin cells contain identical instructions for creating proteins encoded in their DNA, they're able ...
EurekAlert!

Advances in the molecular diagnostic methods for circular RNA

Circular RNA (circRNA) is a unique type of non-coding RNA produced by back splicing of mRNA to form the covalent junction without 3’-5’ polarity and poly(A) tail. CircRNA was first discovered about 30 ...
EurekAlert!

ELAV mediates circular RNA biogenesis in neurons

The ELAV protein binds to specific regions of the precursor RNA, namely to so-called reverse complementary sequences (RCMs) in the introns flanking the "backsplice junction" (BSJ) that is crucial for ...
JSTOR Daily

Genome-wide discovery of natural variation in pre-mRNA splicing and prioritising causal alternative splicing to salt stress response in rice

• Pre-mRNA splicing is an essential step for the regulation of gene expression. In order to specifically capture splicing variants in plants for genome-wide association studies (GWAS), we developed a ...
News Medical

Exploring the role of RNA binding proteins and circular RNAs in cancer

The interaction between RNA-binding proteins (RBPs) and circular RNAs (circRNAs) has emerged as a key area of interest in understanding cancer biology. As critical regulators of gene expression, RBPs ...
JSTOR Daily

Dual roles of the serine/arginine-rich splicing factor SR45a in promoting and interacting with nuclear cap-binding complex to modulate the salt-stress response in Arabidopsis

This is a preview. Log in through your library . Abstract • Alternative splicing (AS) is emerging as a critical co-transcriptional regulation for plants in response to environmental stresses. Although ...