In the microscopic world of bacteria, gene transfer is a powerful mechanism that can alter cellular function, drive ...

A plasmid is a small, circular, double-stranded DNA molecule that is distinct from a cell's chromosomal DNA. Plasmids naturally exist in bacterial cells, and they also occur in some eukaryotes.

To adapt to changing environmental pressures, bacteria have developed various ... is to generate a double-stranded version of the plasmid using rolling circle replication (Figure 1E). The recipient ...

However, he added, "How the first guide was created in the cell is unclear to us at ... proteins that trigger their host bacteria's death to avoid plasmid invasion. Argonautes, however, are ...

Multidrug-resistant bacteria pose a major threat to human health. Manipulation of bacterial genes at the transcriptional level is a potential strategy to fight antibiotic-resistant bacterial ...

In a recent publication in Cell Reports Medicine, a collaborative research team led by Chen-Yu Zhang and Huan Wang at Nanjing ...

However, plasmid copy numbers can fluctuate, causing inconsistent gene expression within bacterial populations ... plasmid copy number within individual cells and the fraction of plasmid-carrying ...

and a single bacterial cell can contain numerous copies of a plasmid. Plasmids also often carry antibiotic resistance genes, which weren’t common in plasmids before the widespread use of ...