Phase I Study of MGCD0103 Given As a Three-Times-Per-Week Oral Dose in Patients With Advanced Solid Tumors We assessed 214 children with acute lymphoblastic leukemia who received 418 courses of oral ...

Potentiated by CYP3A4 inhibitors (eg, ketoconazole, macrolides), cyclosporine, estrogens. Antagonized by CYP3A4 inducers (eg, barbiturates, phenytoin, carbamazepine ...

Dexamethasone may be given prior to chemotherapy to help ease side effects, such as nausea and vomiting. However, it isn’t needed for all types of chemotherapy. Share on Pinterest Patarapol ...

Adjunct Assistant Professor, Department of Psychiatry, Division of Child and Adolescent Psychiatry, Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario, Canada A ...

July 26, 2007 -- Low-dose dexamethasone combined with lenalidomide ( Revlimid, Celgene) gave results superior to those seen with the standard high dose currently used in multiple myeloma in a phase 3 ...

Acute kidney injury can be a serious complication following heart surgery. Patients who received dexamethasone during heart surgery had about a 2.5-times lower risk of developing kidney failure ...

Pharmacologic investigations have not kept pace with the increasing survival of the most immature newborns during the last two decades. Drug therapy for these tiny infants has often been based on ...

When you pop a prescription pill into your mouth, you trust it to address the issue it was meant to fix. But what really happens? How is your body processing the drugs and what happens if the dosage ...