Histone Kla regulates tumor angiogenesis by affecting the levels of downstream HIF1-ɑ and Vegf. In non-histone proteins, YY1-Kla influences FGF2, and Sema3A-Kla affects HIF1-ɑ, both contributing to ...
Chimeric antigen receptor (CAR)-T cell immunotherapy has considerably changed the landscape of treatment options for blood cancers. CAR-T therapy aims to redirect a patient’s T cells to recognize and ...
In this paper, we comprehensively review the role of non-histone protein lactylation in cerebral ischemia–reperfusion (I/R) injury from multiple perspectives, including its dynamic alterations during ...
This Brush Up is sponsored by Cayman Chemical. Learn more about chemical inhibitors of histone modification. Histone modification affects how tightly DNA wraps around histone proteins, yielding ...
This article and associated images are based on a poster originally authored by Banushee Kumar, Alisa Alekseenko, Carmen Navarro and Simon Elsässer and presented at ELRIG Drug Discovery 2025 in ...
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