The faithful replication of the genetic material is essential for normal cell function and genome integrity. Altered DNA bases or DNA structures can block the replication fork generating mutations ...
Apart from the canonical Watson-Crick duplex, nucleic acids can often form other structures, e.g. G-quadruplex and triplex. These structures give nucleic acid additional functions besides coding for ...
DNA, the genetic material compacted in chromosomes, stores information to regulate all the cell processes in the body. Two decades ago, in addition to the widely known Watson-Crick double helix model ...