Early data indicate Voranigo (vorasidenib) is being rapidly adopted in patients with isocitrate dehydrogenase–mutated glioma, ...
Citrate is a critical metabolite required to support both mitochondrial bioenergetics and cytosolic macromolecular synthesis. When cells proliferate under normoxic conditions, glucose provides the ...
Chronic Physical Effects and Health Care Utilization in Long-Term Ovarian Germ Cell Tumor Survivors: A Gynecologic Oncology Group Study Patients were selected according to the following criteria: ...
Figure 1: The overall structure of AceK. Figure 2: The ATP-binding site and the allosteric AMP-binding site in AceK. On the basis of the structural and mutagenesis studies, we rationalize the ...
To assess the effectiveness of manipulating citrate metabolism with the aim of increasing citrate efflux from roots, we generated transgenic tobacco (Nicotiana tabacum L.) lines that either ...
Imetelstat Achieves Meaningful and Durable Transfusion Independence in High Transfusion–Burden Patients With Lower-Risk Myelodysplastic Syndromes in a Phase II Study Twenty-three patients received ...
Disrupted brain fluid clearance in the hemisphere opposite the tumor emerges as a strong independent predictor of survival in ...
The isotrate dehydrogenase (IDH) inhibitors market sales is predicted to expand from US$ 1.7 billion in 2022 to US$ 39.16 billion in 2033, with a compound annual growth rate (CAGR) of 33% from 2023 to ...
The global isocitrate dehydrogenase (IDH) inhibitors market, valued at USD 1.7 billion in 2022, is poised for explosive growth, projected to reach an astounding USD 39.16 billion by 2033. This ...
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