A major psychedelics conference wraps up in Denver today. Its mission is to get more people, especially policy makers, comfortable with what has previously been underground. We speak with the founder ...

Consumption of MDMA, also known as ecstasy, is dropping in Europe, while that of ketamine and cocaine is on the rise. In 2025, residues of MDMA detected in European wastewaters decreased by almost 16% ...

Russia's invasion of Ukraine has killed tens of thousands of Ukrainian soldiers and civilians, and injured hundreds of thousands more. But the war has also taken a less visible toll, with millions ...

MDMA (3,4-methylenedioxymethamphetamine), known colloquially as Molly and Ecstasy, is a synthetic drug with effects similar to stimulants like methamphetamine. It was first synthesized in 1912 by ...

Since emerging in prominence on the party scene in the 1980s, ecstasy has become a staple of festival and rave culture. But the drug also carries far more risks today than it did back then − and some ...

In Sydney, Australia, Rebecca Huntley had been seeking psychiatric care on-and-off for thirty years when she heard from an otherwise straight-edged friend about her experience going through ...

MDMA became widely known in the 1970s for its psychoactive and mood-enhancing properties. Initially popularized as a psychotherapy aid, it later spread as a recreational drug associated with nightlife ...

Vagus-dependent gut–brain signaling inMDMA-induced stress resilience. MDMA elevates central 5-HT and stimulates peripheral release of 5-HT from enterochromaffin cells, alongside oxytocin from ...