For decades, scientists thought the noncoding parts of DNA were useless leftovers. Today, that view has completely changed.

Non-coding DNA variants contribute to acute lymphoblastic leukemia (ALL) chemotherapy resistance. St. Jude Children's Research Hospital scientists have identified specific DNA variants in the non ...

Chimpanzees, along with bonobos, are humans' closest living relatives. In fact, you may have heard that humans and chimps ...

Non-coding DNA variants contribute to acute lymphoblastic leukemia (ALL) chemotherapy resistance. Explore new technology used in the St. Jude-led discovery.

It turns out that the remainder of human DNA in the genome, the non-coding regions, play important roles in regulating and enhancing the protein-coding genes—turning them “on” and “off,” for example.

A new study shows that repetitive DNA, once dismissed as “junk,” plays a critical role in shaping the human brain.

Non-coding DNA had previously been implicated in neurological conditions via several different mechanisms, but the role of strand breaks and their repair is a new finding. According to the study ...

Butterfly wing patterns have a basic plan to them, which is manipulated by non-coding regulatory DNA to create the diversity of wings seen in different species, according to new research.

Scientists have found that non-coding 'junk' DNA, far from being harmless and inert, could potentially contribute to the development of cancer.

This Collection is open to original research examining noncoding DNA in disease, including studies examining the biology of noncoding DNA regions and exploring mutations in noncoding DNA in disease.

Butterfly wing patterns have a basic plan to them, which is manipulated by non-coding regulatory DNA to create the diversity of wings seen in different species, according to new research.

Much of the "junk" DNA in Drosophila shows signs of either negative or positive selection, according to a study in this week's Nature. An analysis by Peter Andolfatto of the University of California, ...