Nature

Rapid quantification of DNA methylation by measuring relative peak heights in direct bisulfite-PCR sequencing traces

Various technologies are currently available to quantify DNA methylation. However, rapid and simple methods for determining the DNA methylation status of CpG sites in genes still remain elusive. In ...
Nature

Optimization of PCR-based minimal residual disease diagnostics for childhood acute lymphoblastic leukemia in a multi-center setting

MRD detection by PCR analysis of rearranged Ig/TCR genes is however a complex process, involving many steps (Figure 1). Identification of pitfalls in this process is of importance in order to ensure ...
Labroots

The Challenges and Advantages of Direct PCR Amplification

Testing for COVID-19 continues to be one of the most important tools in the global fight to slow and reduce the impact of the pandemic, particularly until vaccines are more widely available. Regular ...
Smithsonian Magazine

This Compact PCR Test for Covid-19 Could Give Accurate Results in 15 Minutes

Minute Molecular, the company developing the device, has high hopes for it as an efficient and accurate means of testing people at schools, workplaces and sports stadiums. Northwestern ...