Researchers have been studying tens of thousands of proteins and even more variations without a yardstick to compare their ...

This article and associated images are based on a poster originally authored by Marina Fedorova and Ian Hiles and presented at ELRIG Drug Discovery 2024 in affiliation with GSK. This poster is being ...

Propagation of expression noise from mRNA to protein level is influenced by variation in availability of ribosomal machinery.

The cost-effective, easy-to-use T7 expression system has been integral to Escherichia coli protein production since its introduction in 1986. Now, a just-developed enhancement is making it even better ...

This article is based on a poster originally authored by Sunidhi Shetty, Narasimha Murthy Bandaru, Anna Moberg and Marco Manni, which was presented at ELRIG Drug Discovery 2024 in affiliation with ...

The search space for protein engineering grows exponentially with complexity. A protein of just 100 amino acids has 20100 ...

Extracellular vesicles (EVs) are tiny biological bubbles that carry nucleic acids and proteins between cells, playing an essential role in tissue repair, neuroprotection and immune health. By ...

To enhance CAR T therapies, scientists are actively studying TCR signaling and T-cell exhaustion mechanisms to improve CAR T persistence and function. Additionally, there is a growing trend towards ...

Measuring DLL3 expression via circulating tumor cells (CTCs) may help predict which patients with ES-SCLC will respond to tarlatamab.

Researchers identified three age-related proteins that may play key roles in PH progression as possible treatment targets.