Assistant Professor of Medicine at Harvard Medical School and Associate Physician at Brigham and Women's Hospital, Division of Endocrinology Measurement of renin and its activity is increasingly used ...

Primary aldosteronism (PA) is the most common form of secondary hypertension, caused by hyperactivity in one or both of the adrenal glands that leads to inappropriate aldosterone production. The ...

Fourteen normotensive and 14 hypertensive black men with mild essential low-renin hypertension were examined during two protocols producing sodium depletion (less than 40 mmol sodium diet per day) for ...

THE role of the kidney in the regulation of blood pressure through the mediation of renin was first suggested by the classic experiments of Goldblatt. 1 Although there was considerable initial ...

RENIN is said to split a leucyl–leucine bond in alpha 2 globulin substrate—angiotensinogen—to yield a decapeptide, angiotensin I. Angiotensin I is subsequently converted into an octapeptide, ...