Plants survive cold by adjusting at cellular level. Scientists discovered that the PORCUPINE protein helps plants adapt to ...

"These results far exceeded our expectations for splicing correction following a single dose of PGN-EDODM1. Mis-splicing is the underlying cause of DM1 pathology, and we believe the mean splicing ...

SB-007 addresses the root cause ofStargardt disease with the potential to treat all patients across all ABCA4 mutations SB-007 is the first dual AAV gene therapy in clinical ...

A human-specific NOVA1 variant changed mouse vocalizations, potentially providing insights into the evolution of language.

Stay up to date on the latest science with Brush Up Summaries. Despite its significance, alternative splicing’s global impact on cellular homeostasis and intricate molecular mechanisms remains ...

Identifying splicing-related neoantigens in gliomas opens new avenues for immunotherapy, enhancing treatment strategies for this challenging brain tumor.

Biologists have discovered a new type of RNA-splicing regulation that helps to determine which protein-coding exons will be included in messenger RNA transcripts. RNA splicing is a cellular ...

As climate conditions become increasingly unpredictable, understanding how plants respond to cold is crucial for securing ...

RNA splicing is a cellular process that is critical for gene expression. After genes are copied from DNA into messenger RNA, portions of the RNA that don't code for proteins, called introns, are cut ...

Long-separated twins: at the crossroads of evolution EMBL Grenoble Group Leader Wojciech Galej, who has been working on pre-mRNA splicing machinery for more than 15 years, first decided to focus ...

A pioneering study has uncovered the sophisticated tactics root-knot nematodes use to manipulate the genetic machinery of ...