How does the cell convert DNA into working proteins? The process of translation can be seen as the decoding of instructions for making proteins, involving mRNA in transcription as well as tRNA. But ...

The diagram illustrates the key stages of protein synthesis in a eukaryotic cell. It begins with transcription to produce pre-mRNA in the nucleus (1), followed by post-transcriptional modification (2) ...

What is it that makes a good story, one that catches your attention and refuses to let go? Does it include a peculiar mystery? A well-motivated conflict which craves resolution? A catchy hook? A ...

Researchers from the Wilmer Eye Institute, Johns Hopkins Medicine Center for Nanomedicine—which designs nanotechnology-based ...

In a recent study published in Nature, a group of researchers explored how the incorporation of N1-methylpseudouridine (1-methylΨ) into messenger ribonucleic acids (mRNAs) affects ribosomal ...

Unlocking the potential of mRNA technology is helping revolutionize medicine and biotechnology. Solid-phase in vitro transcription enables scalability and automation, helping make it a valuable tool ...

You don't want to miss this! To permanently access this eBook for free, fill out the short form below. From being a promising yet underexplored approach in the 1990s, mRNA therapeutics have evolved ...

Messenger RNA (mRNA) technology came of age during COVID-19 with several vaccines and therapeutics coming to market. However, since the height of the pandemic, the flow of new mRNA-based products has ...

Although the COVID-19 pandemic brought mRNA-based vaccines to public attention, this method is not new. In 1990, the late Jon Wolfe, PhD, professor of medicine at the University of Wisconsin and ...