Sampson (calf/hand) is not in line to practice Wednesday, Daniel Oyefusi of ESPN.com reports.

Cleveland Browns quarterback Shedeur Sanders will be without two of his primary targets when he faces the Chicago Bears in Week 15.

With many starters not playing on Sunday in Chicago, here are some of the guys who will need to play well for the Cleveland Browns.

Sampson will miss his first game of the season while managing a pair of injuries. His next chance to take the field will come Week 16 against the Bills. As long as Sampson is sidelined, Cleveland's main depth options behind Quinshon Judkins will be Raheim Sanders and Trayveon Williams.

We break down the fantasy football outlook of Dylan Sampson ahead of the Browns’ Week 13 matchup vs. the 49ers.

The Cleveland Browns missed out on a chance to win their fourth game due to miscommunication between Quinshon Judkins and Gage Larvadain. But running back Dylan Sampson opened up about what happened on the play where Judkins held on to the ball,

Browns rookie Dylan Sampson had dealt with a mostly-quiet first season until he hit on a pair of big plays in the Week 12 win over the Raiders.

The Chicago Bears defense will face the Cleveland Browns and their rookie quarterback, Shedeur Sanders. Chicago's defense leads the NFL in takeaways and aims to capitalize on Cleveland's inexperience. The Browns' offense relies heavily on rookie running backs Quinshon Judkins and Dylan Sampson.

Cleveland Browns rookie running back Dylan Sampson made his feelings clear on Shedeur Sanders remaining the quarterback.

Preview the player prop betting lines, stats and more for Dylan Sampson before his Cleveland Browns play the Tennessee Titans in a Week 14 NFL