Nature

A comparison of linear and branched polyethylenimine (PEI) with DCChol/DOPE liposomes for gene delivery to epithelial cells in vitro and in vivo

Linear 22 kDa PEI gives the best transfection efficiency in the mouse airways L-22 kDa, B-25 kDa PEI and DCChol/DOPE lipoplexes were evaluated for luciferase reporter gene delivery to the mouse ...
Nature

L-DNase II activation by the 24 kDa apoptotic protease (AP24) in TNFα-induced apoptosis

As AP24 belongs to the elastase-like family of proteases, it was hypothesized that the missing link between AP24 and DNA degradation could be LEI/L-DNase II. This hypothesis was investigated using ...