Background In 2012, the US Food and Drug Administration approved a Risk Evaluation and Mitigation Strategy (REMS) programme including mandatory prescriber training and a patient/provider ...

Effective improvement and research rely on sustained multidisciplinary collaboration, but few examples are available of centres with the broad range of disciplines and practical experience that are ...

Introduction Quality improvement (QI) efforts are critical to promoting health equity and mitigating disparities in healthcare outcomes. Equity-focused QI (EF-QI) interventions address the unique ...

Several public inquiries into healthcare failings in the UK have noted that employees of failing organizations attempt to raise concerns about shortcomings in care, often over a prolonged period of ...

The semi-literate quotation in the title comes from a note attached to a bomb thrown into Cotton Mather’s house in Boston, Massachusetts on 14 November 1721 because of Mather’s public advocacy of the ...

Healthcare institutions continue to face challenges in providing safe patient care in increasingly complex organisational and regulatory environments while striving to maintain financial viability.

Background With the introduction of Computerised Physician Order Entry (CPOE) in routine hospital care, a great deal of effort has been put into refining Clinical Decision Support Systems (CDSS) to ...

Objectives To document the burden of in-hospital falls and fractures, and to identify factors that may increase the risk of these events. Design A retrospective cohort analysis Setting The study was ...

The 1999 Institute of Medicine report raised public awareness of the frequency and cost of adverse drug events in medicine. In response, in November 2000 a coalition of healthcare purchasers announced ...

Doing ‘detective work’ to find a cancer: how are non-specific symptom pathways for cancer investigation organised, and what are the implications for safety and quality of care? A multisite qualitative ...

Do good without fear and tell the truth. For Henry Beecher, this was both wisdom and paradox. Reality and perception are not always the same. Beecher was born in Peck, Kansas in 1904 with the birth ...

High risk industries such as commercial aviation and the oil and gas industry have achieved exemplary safety performance. This paper reviews how they have managed to do that. The primary reasons are ...