Mucosal administration of ETH47, an LNP-formulated IFNλ1-encoding mRNA, in mice increases immune defense and survival after ...
ASC scaffolds and cross-seeds Aβ amyloid and is considered an actionable target against Alzheimer’s disease. This study ...
In this study we show that Dantrolene, an approved ryanodine receptor antagonist, improved various pathophysiological ...
In eukaryotes, DNA is packaged into chromatin with the help of highly conserved histone proteins. Together with DNA-binding proteins, posttranslational modifications (PTMs) on these histones play ...
These specks play a vital role in the pro-inflammatory response by maximizing IL-1 maturation, and facilitating pyroptosis, an inflammatory type of cell death characterized by plasma membrane rupture ...
Identification of resistance mechanisms to small-molecule inhibition of TEAD-regulated transcription
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The Hippo tumor suppressor pathway controls ...
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Cerebral palsy (CP) is a prevalent ...
An ancient role for CYP73 monooxygenases in phenylpropanoid biosynthesis and embryophyte development
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and ...
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Adult neural stem cells (NSCs) in the ...
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