One NFL team will be without two of its biggest stars for a critical game this weekend as it fights for playoff positioning.

With news that Brock Purdy is out for San Francisco, the spread for Sunday's showdown at Green Bay has moved. Here are odds, ...

Quarterback Brock Purdy and defensive end Nick Bosa are not available for the San Francisco 49ers as they enter Green Bay ...

Douglas lost his job as the general manager on Tuesday, six weeks after the head coach was replaced following a 2-3 start.

Brock Purdy and Nick Bosa are not available for the San Francisco 49ers when they enter Green Bay with designs on finding ...

Philadelphia Eagles (8-2) at Los Angeles Rams (5-5), 3:20 p.m. HST, NBC ...

San Francisco quarterback Brock Purdy will miss Sunday’s game against the Green Bay Packers with a sore throwing shoulder, ...

Brandon Allen will start in place of an injured Brock Purdy when the 49ers (5-5) also have to play without Nick Bosa on ...

The San Francisco 49ers will be without their starting quarterback and their best defensive player when they visit the Green ...

The Green Bay Packers could be facing Brandon Allen instead of Brock Purdy when they host the San Francisco 49ers on Sunday.

It's officially time to be massively concerned for the San Francisco 49ers. Head coach Kyle Shanahan has officially ruled out ...