The cast of “Dawson’s Creek” is set to reunite for the first time since the WB drama went off the air in 2003 after a six season run. In its entirety, the stars of the beloved series will come together at the Richard Rodgers Theatre for a charity event on Sept. 22 for a partnership with F Cancer.

James Van Der Beek, Katie Holmes, Joshua Jackson, Michelle Williams and the rest of the "Dawson's Creek" cast will reunite for the first time in more than two decades.

The stars of "Dawson's Creek" will reunite for a benefit event intended to support F Cancer and actor James Van Der Beek, who has been battling the disease.