Isaac Guerendo had a 76-yard run in the fourth quarter to help the San Francisco 49ers defeat the Seattle Seahawks, 36-24.
Isaac Guerendo purposely bailed on what would have been a game-sealing touchdown against the Seahawks on "Thursday Night ...
In his best game of the season -- last week versus the Arizona Cardinals -- Isaac Guerendo finished with 2.2 fantasy points.
Deebo Samuel shared a playful response to Isaac Guerendo after the 49ers rookie running back didn't score his first NFL ...
The 49ers running back room is depleted after Jordan Mason suffered a shoulder injury on "Thursday Night Football." ...
San Francisco's Isaac Guerendo seals the 49ers' win with a 76-yard run in the final two minutes, then Kyle Juszczyk scores to ...
In his best game of the season, Isaac Guerendo finished with 1.9 fantasy points -- 5 carries, 19 yards. That was in Week 3 ...