Ever since making the switch from high school receiver to running back in college, Isaac Guerendo has had few opportunities ...

Running back Christian McCaffrey is on injured reserve for the second time this season, but San Francisco 49ers coach Kyle ...

Christian McCaffrey's injury-ridden season took another unfortunate turn when the star running back went down with another ...

Christian McCaffrey practiced little and played less this season, seeing action in four games with 65 touches. He is out for the season with his knee injury that will require a six-week recovery.

McCaffrey immediately checked himself out of the game and ran right into the medical tent. The 49ers star RB missed the ...

San Francisco 49ers star Christian McCaffrey recently took to social media to send fans and supporters a message about his ...

San Francisco 49ers running back Christian McCaffrey reflected on his 2024 NFL season that fell short of expectations with a ...

Christian McCaffrey suffered a PCL injury in the 49ers' Week 13 loss to the Bills. He addressed the injury on social media ...

The running back position took a massive hit in Week 13 for the San Francisco 49ers. Christian McCaffrey (knee) and Jordan Mason (ankle) sustained injuries in t ...

San Francisco 49ers running back Christian McCaffrey made his season debut less than one month ... shared his initial ...

Isaac Guerendo will make his first NFL start on Sunday as the injury-depleted San Francisco 49ers face the Chicago Bears. The ...

Slow motion video shows where 49ers running back Christian McCaffrey seemingly injured himself and ended his season.