The EMBO Journal2h
Gene therapy for epilepsy targeting neuropeptide Y and its Y2 receptor to dentate gyrus granule cells
Co-expressing NPY and its inhibitory receptor Y2 in excitatory hippocampal cells allows inhibitory autoregulation of ...
The EMBO Journal3d
HIV-1 Vpu induces neurotoxicity by promoting Caspase 3-dependent cleavage of TDP-43
HIV-1 Vpu triggers the cleavage of TDP-43 by stimulating Caspase 3 activation. The cleavage products generated can induce the ...
The EMBO Journal3d
Next generation of “magic bullets”, solutions from the microbial pangenome
These toxins provide new tools for precision cancer medicine, bringing us closer to the elusive “magic bullet.” In addition, ...
The EMBO Journal3d
Histamine synthesis and transport are coupled in axon terminals via a dual quality control system
Neurotransmitters are key for synaptic transmission at axon terminals, but their transport modalities remain debated. This ...
The EMBO Journal5d
An hepatitis B and D virus infection model using human pluripotent stem cell-derived hepatocytes
This study presents human pluripotent stem cell-derived hepatocyte-like cells (HLCs) as a culture system that expands the ...
The EMBO Journal3d
Activation of an atypical plant NLR with an N-terminal deletion initiates cell death at the vacuole
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Plants evolve nucleotide-binding leucine-rich ...
The EMBO Journal5d
Disordered regions in the IRE1α ER lumenal domain mediate its stress-induced clustering
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Conserved signaling cascades monitor ...
The EMBO Journal6d
Elucidating the assembly of gas vesicles by systematic protein-protein interaction analysis
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Gas vesicles (GVs) are gas-filled microbial ...
The EMBO Journal3d
The influence of AHR on immune and tissue biology
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The aryl hydrocarbon receptor is a ligand ...
The EMBO Journal3d
Molecular mechanism of β-arrestin-2 pre-activation by phosphatidylinositol 4,5-bisphosphate
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The mechanism of β-arrestin (βarr2) ...