Medical researchers have discovered that semaglutide may reverse the debilitating tissue damage caused by osteoarthritis, the world's most common form of arthritis. The drug behind Ozempic and Wegovy ...

Respiratory supercomplex formation relieves molecular strain of mitochondrial membranes and reshapes global protein motions, linking membrane reorganization to respiratory function.

Mitochondria are the body's "energy factories," and their proper function is essential for life. Inside mitochondria, a set of complexes called the oxidative phosphorylation (OxPhos) system acts like ...

Mitochondria are known as the body’s “energy factories,” and their function is essential for life. Inside mitochondria, a set of complexes called the oxidative phosphorylation (OxPhos) system ...

Marina Rosa Moreno, Fátima Sánchez Cabo, José Luis Cabrera, José Antonio Enríquez, María Concepción Jiménez, Pablo Hernansanz Agustín and Lucía Sánchez-García. Mitochondria are the body’s “energy ...

Sarcomas are generally classified into soft tissue sarcomas, such as fibrosarcoma, and bone sarcomas such as chondrosarcoma, which are rare cancers in adults accounting for about 1% of all cancer ...

Translocation renal cell carcinoma (tRCC) is an aggressive subtype of kidney cancer driven by TFE3 gene fusions, which act via poorly characterized downstream mechanisms. Here we report that TFE3 ...

Researchers uncovered a mechanism called excitation-mitochondrial DNA transcription coupling (E-TCmito) linking neuronal activity to mitochondrial DNA transcription, crucial for maintaining brain ...

HIGH-GRADE serous ovarian cancer (HGSOC) exhibits two distinct metabolic subtypes, with high oxidative phosphorylation (OXPHOS) tumours showing greater chemosensitivity and low OXPHOS tumours ...

Revolutionary imaging technique uncovers metabolic differences in ovarian cancer subtypes, paving the way for early detection and personalized treatment strategies. Study: Metabolic imaging ...