In May, an episode of the popular cartoon comedy joked about the ongoing trend surrounding weight loss drugs. In the show, Eric is prescribed the drug Lizzo, which was called a “whole new obesity drug for those of us who can’t afford Ozempic and Mounjaro.”

On Monday, the 36-year-old shared multiple Instagram posts showing herself as a red and white package resembling a fictional weight-loss drug called Lizzo, with a yellow measuring tape wrapped around her waist. Last month, Lizzo, whose full name is Melissa Viviane Jefferson, denied rumors that her recent weight loss was due to using Ozempic.

Lizzo dressed up in an Ozempic-themed Halloween costume as the singer poked fun at an episode of "South Park" that parodied her earlier this year.

Lizzo continues to embrace and spin the ’South Park’ Ozempic joke as she dresses up as the phony weight loss drug ‘Lizzo’ from the episode for Halloween.

Lizzo has poked fun at ongoing rumours surrounding her weight loss with her bold choice of Halloween costume. Rumour has it the Grammy winner used the diabetes medicine Ozempic to drop the kilos in recent months, accusations she has rubbished.

Lizzo has taken a rather silly reference to her on a recent “South Park” episode and elevated it to a hilarious Halloween costume.

Lizzo is getting in on the joke with a new Halloween costume that spoofs a bit from South Park: The End of Obesity, a TV special of the animated Comedy Central sitcom that referenced the musician and the diabetes drug Ozempic used for weight loss.

Lizzo is officially kicking off Halloween 2024 with a creative new costume. On Saturday (Oct. 25), the pop-rap sensation took to Instagram to showcase her self-described "LizzOzempic" outfit, inspired by a recent episode of South Park.

Earlier this year, the Comedy Central cartoon made a joke about the singer in an episode about Ozempic and other weight loss drugs