Background In 2012, the US Food and Drug Administration approved a Risk Evaluation and Mitigation Strategy (REMS) programme including mandatory prescriber training and a patient/provider ...

Background Literature depicts differences in ethical decision-making (EDM) between countries and intensive care units (ICU). Objectives To better conceptualise EDM climate in the ICU and to validate a ...

Purpose Misgendering of transgender and non-binary (TGNB) individuals in healthcare settings can lead to worsened mental and physical health outcomes and decreased utilisation of care. Few studies ...

More than 20 years since a landmark study1 documented hospitalised patients were more likely to die when their nurse cared for too many patients at a time, hundreds of rigorously conducted studies in ...

Choosing Wisely (CW) identifies low-value, wasteful medical interventions whose elimination increases the quality of care and likely reduces its costs.1 Since its launch in 2012, this grassroot ...

‘We need bold, fundamental change that gets at the roots of the burnout crisis.’ - US Surgeon General Vivek H. Murthy, MD, MBA. Well-being was brought into clearer focus during the COVID-19 pandemic, ...

Background Differences in contexts (eg, policies, healthcare organisation characteristics) may explain variations in the effects of patient safety practice (PSP) implementations. However, knowledge of ...

The emergency department (ED) abounds with hazards that might lead to adverse events (AEs). Clinicians must make frequent, high-consequence decisions with high diagnostic uncertainty as part of ad hoc ...

Sepsis remains a leading cause of morbidity and mortality worldwide.1 The use of artificial intelligence (AI), and particularly machine-learning (ML) approaches, to predict which patients are at risk ...

Tackling overuse in healthcare is now more necessary than ever. Movements such as Choosing Wisely and Preventing Overdiagnosis have highlighted that some healthcare services offer no added value and ...

Background Improving small and sick newborn care (SSNC) is crucial in resource-limited settings. Newborn Essential Solutions and Technologies (NEST360), a multicountry alliance, aims to reduce newborn ...

For patients in the intensive care unit (ICU), prolonged mechanical ventilation is associated with poor outcomes. A quality improvement (QI) initiative with the aim of reducing median time on the ...