UroToday2d
ASTRO 2024 Featuring Validation of Digital Pathology MMAI Algorithm and of the Decipher® Genomic Testing in the VANDAAM Study
Yang Song presented findings on the ArteraAI Prostate Test, a digital pathology multimodal artificial intelligence (MMAI) algorithm, which was shown to predict overall survival in patients with ...
UroToday4d
2024 Revised Dutch guidelines for urinary incontinence: Addressing clinical bottlenecks through a modular approach
The Dutch Urological Association (NVU) has revised its guidelines for the treatment of urinary incontinence (UI) in secondary and tertiary care, updating the 2014 guidelines to address specific ...
UroToday4d
Does the Extent of Transurethral Resection after Radiation Therapy Impact Survival Outcomes in Muscle-Invasive Bladder Cancer - Expert Commentary
A current standard of care treatment for muscle-invasive bladder cancer (MIBC) is platinum-based neoadjuvant chemotherapy (NAC) followed by radical cystectomy (RC). Bladder-sparing protocols are ...
UroToday4d
Integrated multi-omics assessment of lineage plasticity in a prostate cancer patient with brain and dural metastases.
Metastases to the brain are rare in prostate cancer. Here, we describe a patient with two treatment-emergent metastatic lesions, one to the brain with neuroendocrine prostate cancer (NEPC) histology ...
UroToday4d
Aristolochic acid-related renal cell carcinoma exhibits a distinct tumor-immune microenvironment favoring response to immune checkpoint blockade.
Immune checkpoint blockade (ICB) is currently the standard of care for metastatic renal cell carcinoma (RCC), but treatment responses remain unpredictable. Aristolochic acid (AA), a prevalent ...
UroToday4d
Patient Demographics and Major Adverse Cardiovascular Events after Androgen Deprivation Therapy for Prostate Cancer
Background. The association between patient demographics and CV events after ADT using real-world data was evaluated. In addition to encompassing >30 times more patients than all previous MACE studies ...
UroToday4d
Tranexamic Acid During Radical Cystectomy: A Randomized Clinical Trial.
Among cancer surgeries, patients requiring open radical cystectomy have the highest risk of red blood cell (RBC) transfusion. Prophylactic tranexamic acid (TXA) reduces blood loss during cardiac and ...
UroToday4d
Benefit of Whole-Pelvis Radiation for Patients With Muscle-Invasive Bladder Cancer: An Inverse Probability Treatment Weighted Analysis.
The value of pelvic lymph node irradiation is debated for patients with muscle-invasive bladder cancer (MIBC) undergoing curative-intent radiation therapy (RT). We sought to compare the oncological ...
UroToday4d
Multivariate analysis of the parameters affecting the choice of surgical treatment for patients with localized renal cell carcinoma (RCC).
to determine the key factors affecting the surgical treatment selection for patients with localized Renal-Cell Carcinoma (RCC) based on clinical and nephrometry data. A retrospective cohort study to ...
UroToday4d
PSMA PET/CT patterns of recurrence after mono-brachytherapy in men with low and intermediate prostate cancer and subsequent management.
Brachytherapy as monotherapy is a recommended treatment option for men with low to intermediate risk prostate cancer. Local recurrence is difficult to identify. This study investigated PSMA PET/CT for ...
UroToday4d
Prostate Specific Antigen and Prostate Cancer in Gender Affirming Hormone Therapy for Transgender or Nonbinary Individuals.
The effects of gender affirming hormone therapy on prostate specific antigen (PSA) and prostate cancer incidence in transgender or non-binary individuals (TGNB) born with prostate glands remains ...
UroToday4d
Heterogeneous genetic architectures of prostate cancer susceptibility in sub-Saharan Africa.
Men of African descent have the highest prostate cancer incidence and mortality rates, yet the genetic basis of prostate cancer in African men has been understudied. We used genomic data from 3,963 ...