Barry Manilow, 82, will undergo surgery to remove a cancerous spot on his lung. January concerts rescheduled. Recovery ...

Powerball jackpot soars to $1.7 billion after 46th drawing without a winner. Odds of 1 in 292.2 million. Next drawing on ...

Expect light rain and drizzle this morning, with clearing skies and a significant temperature drop tonight. Colder air to ...

INDIANAPOLIS (WISH) — The Colts lost to the 49ers, 48-27. The loss dropped the team’s record to 8-7 and marked their fifth ...

Chemical explosion at The Heritage Group in Indianapolis leaves one person seriously injured. Firefighters working to ...

The loss drops the Colts to 8-7, and it is their fifth straight loss. The Colts trailed 24-17 at halftime. Next up for the ...

Georgia Street Rhythm & Blues Lounge in Indianapolis now restricts entry to those 30 and older, aiming to create a more ...

Jaylen Brown's 31-point performance leads Boston Celtics to a comeback victory over Indiana Pacers. Celtics win their third ...

U.S. military strike on alleged drug boat in Pacific Ocean kills one. Operation Southern Spear aims to curb narcotics ...

Colts trail 49ers 24-17 at halftime. Philip Rivers threw 2 TDs, but the Colts defense struggles. 49ers to receive the ball in ...

Novo Nordisk's weight-loss pill, Wegovy, has been approved by the FDA, giving the company a competitive edge in the market ...

Woman in critical condition after assault at Indianapolis apartment complex. Police investigating, no suspect information ...