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MOA of Fever (Pyrexia) in Points Fever = regulated rise in body temperature due to an increased hypothalamic set point. Infection/inflammation occurs. Immune cells release pyrogenic cytokines: IL-1 IL-6 TNF-α These cytokines stimulate production of Prostaglandin E2 (PGE2). PGE2 acts on the hypothalamus and raises the temperature set point. The body now perceives its current temperature as too low. Vasoconstriction reduces heat loss. Shivering increases heat production. Metabolic activity increas
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Prostaglandins are lipid-like compounds that contribute to period pain & are typically released the week before your period. Anti-inflammatory foods can help decrease these chemicals to help improve your period! Below are specific nutrients & superfoods that have been shown to help… 👉🏼 vitamin E (PMID: 36513486) like avocado, almonds, olive oil & sunflower seeds 👉🏼 3 whole eggs. Eggs are rich in vitamin D, which can help reduce prostaglandins and inflammation (PMID: 38613122). Add to avocado
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