CAR-NK cells vs breast cancer 🧑‍🔬 🔬 Live-cell imaging captures HER2-targeted CAR-NK cells eliminating breast cancer organoids - showing how engineered immune cells can destroy tumors in real time. 🦠 Natural killer (NK) cells are innate immune cells capable of eliminating abnormal cells. In this study, they were engineered with a chimeric antigen receptor (CAR) to specifically target HER2/ErbB2, often overexpressed in aggressive breast cancers. 🧫 Researchers used patient-derived cancer organ
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CAR-NK cells vs breast cancer 🧑‍🔬 🔬 Live-cell imaging captures HER2-targeted CAR-NK cells eliminating breast cancer organoids - showing how engineered immune cells can destroy tumors in real time. 🦠 Natural killer (NK) cells are innate immune cells capable of eliminating abnormal cells. In this study, they were engineered with a chimeric antigen receptor (CAR) to specifically target HER2/ErbB2, often overexpressed in aggressive breast cancers. 🧫 Researchers used patient-derived cancer organ
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Ever wondered how tumors escape the immune system? 🧑‍🔬 In this video, NK (natural killer) cells chase down and try to eliminate cancer cells by injecting a deadly enzyme: granzyme B. Normally, this would trigger cell death… but tumors have evolved clever survival tricks. 🥷🏿 NK cells deliver granzyme B into tumor cells - a crucial step in immune-mediated killing. However, tumor cells have found a way to fight back. They activate autophagy - a process where cells break down and recycle their o
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Christin Hart on Instagram: "Did you know that your immune system has specialized cells designed to fight cancer? Let’s break down how T cells and natural killer (NK) cells are created and activated to help protect your body! 💪 🧬 How They’re Made: 1. Hematopoiesis: All white blood cells, including T cells and NK cells, start from hematopoietic stem cells in the bone marrow. These stem cells differentiate into different types of immune cells. 2. T Cells: - Journey to the Thymus: Progenitor cell
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