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Ayahuasca is an extract from the vine Banisteriopsis caapi, used in spiritual rituals in South America. When mixed with leaves containing DMT, it produces a strong hallucinogenic effect. DMT is rapidly broken down by the enzyme monoamine oxidase when ingested, unless an inhibitor of this enzyme is present. The harmala alkaloids in B. caapi, typically harmine and harmaline, are β-carbolines that inhibit monoamine oxidase. In this exercise, complete the synthesis scheme for harmine and harmaline.
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Ayahuasca is an extract from the vine Banisteriopsis caapi, used in spiritual rituals in South America. When mixed with leaves containing DMT, it produces a strong hallucinogenic effect. DMT is rapidly broken down by the enzyme monoamine oxidase when ingested, unless an inhibitor of this enzyme is present. The harmala alkaloids in B. caapi, typically harmine and harmaline, are β-carbolines that inhibit monoamine oxidase. In this exercise, complete the synthesis scheme for harmine and harmaline.
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