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Medicine Mondays: Cushing’s Disease, Part 2 Now that we’ve talked about how to diagnose Cushing’s, Part 2 is all about differentiating the two main forms. Most dogs have pituitary-dependent Cushing’s, where a pituitary tumor overstimulates both adrenal glands. A smaller percentage have adrenal-dependent disease, caused by a cortisol-secreting adrenal tumor acting independently. In this video, I walk through how we tell the difference using hormone testing patterns, endogenous ACTH, and imaging,
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Happy Friday! Today's Clinical Cut is all about Cushing syndrome. Cushing syndrome, named after the famous neurosurgeon, Harvey Cushing who first described it, is an endocrine disorder with elevated cortisol levels in the blood. In some cases, Cushing syndrome results from a pituitary adenoma making excess ACTH, and in those situations it’s called Cushing disease. In Cushing syndrome, cortisol levels are constantly higher than normal, so its effects are exaggerated. Excess cortisol leads to seve
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